So, 5-alpha-reductase inhibitors are only helpful when you’re using other steroids (like testosterone) that can convert to DHT. Doses of 1.25 to 2.5 daily are more than sufficient to mitigate estrogenic side effects on the cycle. When these two hormones are increased, so too are your testosterone levels. Starting Clomid in post-cycle therapy two weeks after your steroid cycle ends is most recommended. There was a statistically significant improvement in testosterone levels, from 309 ng/dL to 642 ng/dL 3 months after initiation of therapy. Due to its mechanism of action of increasing gonadotropin levels, clomiphene is less effective in raising testosterone levels in men who already have elevated LH levels prior to the initiation of treatment. When the goal is to increase circulating testosterone levels in a patient with low testosterone levels, there are a number of reasons that make clomiphene therapy a more practical choice than conventional testosterone replacement therapy. It is unclear how it stops cancer cells from growing, but it appears to compete for hormone receptor sites in the cells. Like SERMs, these drugs attach to estrogen receptors. These drugs are known as selective estrogen receptor modulators (SERMs). 5-alpha-reductase inhibitor drugs will block this enzyme, reducing your DHT levels. If your steroid cycle includes only very low doses of Nandrolone, you might be able to use Vitamin B6 as the only anti-progestogenic ancillary. A daily Pramipexole dose between 0.125mg and 0.25mg is effective at preventing gyno, lactation, and sexual dysfunction caused by high prolactin levels. Cabergoline is probably the most used dopamine agonist among anabolic steroid users. Dopamine agonist drugs will stimulate the dopamine receptors and have the effect of lowering prolactin levels. HCG can bring on some estrogenic and androgenic side effects at higher doses. Gyno is typically caused by increased estrogen, and the goal of Gynectrol is to restore the balance of your hormones so that testosterone takes its rightful place at optimal levels. On-cycle use of Nolvadex to protect against male breast enlargement is an established anabolic steroid user protocol. When AIs work to inhibit aromatase, effects like gyno are reduced, and testosterone levels rise. You’ll also discover essential anti-estrogenic, anti-androgenic, and anti-progestogenic ancillaries, and I’ve included some tried and tested PCT protocols to get you going. On the other hand, you can do plenty of proactive things while on-cycle to help your recovery later. But times have changed, and we now have access to good quality and relatively safe drugs for PCT purposes2.
