At Voy, we use 29G or 27G needles for injecting testosterone, as these are smaller needles which tend to be more comfortable. We would say that the morning would be traditionally is the best time for testosterone injections. Rotating injection sites helps to ensure your medication is absorbed into your body and to reduce skin damage. Proper preparation ensures safety and accuracy for your testosterone injections. Ask your pharmacist or healthcare provider to familarize you with the injection process. Talk to your pharmacist about the correct length and gauge of needles to accurately and safely administer your injection. This is because testosterone is held within oil which makes it more viscious and thicker. Testosterone can be tougher to inject than other substances such as insulin. Store your medication at the recommended temperature because it can damaged by sunlight Inject the medication in a steady, controlled pace. Select a location on your belly that is at least 2 inches from your belly button, then pinch an inch of skin and fatty tissue between your fingers. Subcutaneous shots go directly into the fatty tissue beneath the dermal and epidermal layers of the skin. Subcutaneous shots go right under the skin, making it easier to self-administer. TESTOSTERONE (tes TOS ter one) is used to increase testosterone levels in your body. Noble Health Clinic offers a range of medical services, including preventive care, diagnostic testing, treatment for acute and chronic illnesses, and minor surgical procedures. Our team of experienced healthcare professionals has been guiding patients through the TRT process for years, and we’re here to ensure your journey is smooth and worry-free. Testosterone therapy comes in different forms, but self-injection is one of the most common and reliable options. Yes, you can inject testosterone before bed, or any time of day that’s convenient for you. Shorter-acting esters often require two or three weekly injections to smooth out hormone fluctuations. An IM (intramuscular) injection is too shallow and misses the muscle, it can harm the surrounding tissues. I sometimes get a lump at the injection sight. How to give yourself a testosterone IM injection. Self-injection is completely safe when it is properly prescribed, under the supervision and guidence of your doctor. Most patients feel anxious when it comes to inject themselves with needles. Talk with your doctor about your anxiety for self-injections is an important step to making this process doable.