The diagnosis often included blood tests showing testosterone below the average range. Athletic commissions, which regulate MMA competitions to ensure fair play and fighter safety, allowed TRT in certain cases. Testosterone Replacement Therapy (TRT) in mixed martial arts (MMA) became one of the most controversial topics in the sport’s history. However, the performance gains linked to TRT eventually led to discussions and eventual changes in regulations, as many began to feel that TRT shifted the balance of fair competition in MMA. Furthermore, TRT may aid in recovery from larger injuries that can take fighters out of action. Testosterone helps repair these tissues faster, which means fighters on TRT can train more often and at higher intensities without becoming as sore or tired. Celebrity boxer and influencer Armz Korleone tested for T/E levels at 34/1, 1/1 is normal. The twist is that no other sport appears to have so freely handed out passes to TRT. Despite his current hardened stance, Bisping said he likely would not have balked at challenging Belfort even had he known of his testosterone supplementation. Coming two years after Belfort now acknowledges having begun TRT, the release said the regimen had been initiated after a diagnosis of "hypogonadism, or low testosterone." Only a month after the fight, amid a firestorm of rumors, the UFC issued a statement revealing Belfort had been on a medically approved TRT regimen under the supervision of a Nevada physician. The rise and fall of TRT in MMA shows how sports evolve to address new challenges. For many fans and fighters, this change was a necessary step toward keeping the sport fair and protecting the integrity of competition. His case highlighted the potential for TRT to enhance performance, sparking questions about fairness and the true purpose of therapeutic exemptions. Belfort’s association with TRT and the events surrounding it played a major role in shaping MMA’s stance on hormone therapy. Other athletic commissions, including those in California and Brazil, soon followed Nevada’s lead, creating a ripple effect in MMA. His performances after the ban were inconsistent; he won some fights but also suffered several losses, often against top-ranked opponents who were younger or physically more resilient. He struggled against younger, physically dominant opponents who could maintain higher levels of output throughout the fight. His previous fighting style relied heavily on bursts of power and aggression, which were supported by the physical benefits he gained from TRT. Nor is the fiery Brit the lone voice of suspicion in a sport in which doping has evolved through the years -- as in many others -- from hard-core steroids to growth hormone and designer drugs. But whether naive or merely oblivious to the rumor mill, 34-year-old Bisping claims he was ignorant of his past opponents' testosterone exemptions when he stepped in the octagon. The only definitive way to make such an observation is to autopsy brains after death, and an expert in the study of chronic traumatic encephalopathy in athletes indicated research to date had recorded no such hormone deficiencies. As for MMA fighters, medical experts question the logic of allowing someone diagnosed as suffering head trauma to step back in an MMA octagon. "If I don't do it testosterone-replacement therapy, I am actually at a disadvantage. People don't know that." Sparring, weightlifting, and cardiovascular conditioning can all cause small injuries or "micro-tears" in muscles. Recovery time is a critical factor in MMA because fighters undergo intense training sessions that push their bodies to the limit. Testosterone helps increase red blood cell production, which in turn improves oxygen delivery to muscles. Endurance and stamina are essential for MMA fighters, who often face rounds lasting several minutes and must perform at their peak without tiring. Testosterone is a hormone produced mainly in the testes in men and, in smaller amounts, in the ovaries in women. These supplements often contain natural ingredients believed to support the body’s testosterone production. This supports the notion that more demanding workouts, involving more sets, reps, and heavier weights, can significantly amplify testosterone release.